clonal deletion meaning in English

克隆排除
克隆缺失

Transplantation has been developed to an effctive strategy for treatment of end stage diseases of multiple organs since 1950 ' s . despite success of current immunosuppressive drugs , transplantation immunologists and surgeons are still seeking to achieve tolerance to allograft . there are several different mechanisms such as clonal deletion , anergy , neglect , immuno regulation . which maintain tolerance to self - antigen . some strategies , derived from these mechanisms has been proved to be encouraged in suppression of allograft rejection
二十世纪五十年代以来，器官移植的进展使同种异体器官移植成为治疗多种器官终末期疾病的有效手段。尽管目前免疫抑制方案非常有效，但免疫耐受仍是移植免疫学家和外科医生关注的课题。有多个机制使免疫系统对自身抗原保持耐受，如：克隆清除、忽略、失能、免疫调节。